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1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data

We hypothesize that imputation based on data from the 1000 Genomes Project can identify novel association signals on a genome-wide scale due to the dense marker map and the large number of haplotypes. To test the hypothesis, the Wellcome Trust Case Control Consortium (WTCCC) Phase I genotype data we...

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Detalhes bibliográficos
Main Authors: Huang, Jie, Ellinghaus, David, Franke, Andre, Howie, Bryan, Li, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376268/
https://ncbi.nlm.nih.gov/pubmed/22293688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.3
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