Real-Time Monitoring of Tumorigenesis, Dissemination, & Drug Response in a Preclinical Model of Lymphangioleiomyomatosis/Tuberous Sclerosis Complex

BACKGROUND: TSC2-deficient cells can proliferate in the lungs, kidneys, and other organs causing devastating progressive multisystem disorders such as lymphangioleiomyomatosis (LAM) and tuberous sclerosis complex (TSC). Preclinical models utilizing LAM patient-derived cells have been difficult to es...

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Autors principals: Liu, Fangbing, Lunsford, Elaine P., Tong, Jingli, Ashitate, Yoshitomo, Gibbs, Summer L., Yu, Jane, Choi, Hak Soo, Henske, Elizabeth P., Frangioni, John V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376142/
https://ncbi.nlm.nih.gov/pubmed/22719903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038589
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