Prenatal Arsenic Exposure Alters Gene Expression in the Adult Liver to a Proinflammatory State Contributing to Accelerated Atherosclerosis

The mechanisms by which environmental toxicants alter developmental processes predisposing individuals to adult onset chronic disease are not well-understood. Transplacental arsenic exposure promotes atherogenesis in apolipoprotein E-knockout (ApoE(−/−)) mice. Because the liver plays a central role...

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Main Authors: States, J. Christopher, Singh, Amar V., Knudsen, Thomas B., Rouchka, Eric C., Ngalame, Ntube O., Arteel, Gavin E., Piao, Yulan, Ko, Minoru S. H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376138/
https://ncbi.nlm.nih.gov/pubmed/22719926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038713
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