Reduced Anxiety and Depression-Like Behaviours in the Circadian Period Mutant Mouse Afterhours

BACKGROUND: Disruption of the circadian rhythm is a key feature of bipolar disorder. Variation in genes encoding components of the molecular circadian clock has been associated with increased risk of the disorder in clinical populations. Similarly in animal models, disruption of the circadian clock...

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Detalhes bibliográficos
Main Authors: Keers, Robert, Pedroso, Inti, Breen, Gerome, Aitchison, Kathy J., Nolan, Patrick M., Cichon, Sven, Nöthen, Markus M., Rietschel, Marcella, Schalkwyk, Leonard C., Fernandes, Cathy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376117/
https://ncbi.nlm.nih.gov/pubmed/22719873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038263
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