Clinical Efficacy and Safety of Bevacizumab Monotherapy in Patients with Metastatic Melanoma: Predictive Importance of Induced Early Hypertension

BACKGROUND: VEGF driven angiogenesis plays a key role in cancer progression. We determined the clinical efficacy of bevacizumab monotherapy in patients with metastatic melanoma. METHODS AND FINDINGS: Thirty-five patients with metastatic melanoma in progression were enrolled in this phase II, single...

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Main Authors: Schuster, Cornelia, Eikesdal, Hans P., Puntervoll, Hanne, Geisler, Jürgen, Geisler, Stephanie, Heinrich, Daniel, Molven, Anders, Lønning, Per E., Akslen, Lars A., Straume, Oddbjørn
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376108/
https://ncbi.nlm.nih.gov/pubmed/22719881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038364
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