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Spatial structure increases the waiting time for cancer

Cancer results from a sequence of genetic and epigenetic changes which lead to a variety of abnormal phenotypes including increased proliferation and survival of somatic cells, and thus, to a selective advantage of pre-cancerous cells. The notion of cancer progression as an evolutionary process has...

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Detalhes bibliográficos
Main Authors: Martens, Erik A., Kostadinov, Rumen, Maley, Carlo C., Hallatschek, Oskar
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375912/
https://ncbi.nlm.nih.gov/pubmed/22707911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1367-2630/13/11/115014
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