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BLUP Genotype Imputation for Case-Control Association Testing with Related Individuals and Missing Data

We consider the problem of case-control association testing in samples that contain related individuals, where we assume the pedigree structure is known. Typically, for each marker tested, some individuals will have missing genotype data. The MQLS method has been proposed for association testing in...

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Detalhes bibliográficos
Autor principal: McPeek, Mary Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375641/
https://ncbi.nlm.nih.gov/pubmed/22697245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0024
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