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Constructing patch-based ligand-binding pocket database for predicting function of proteins

BACKGROUND: Many of solved tertiary structures of unknown functions do not have global sequence and structural similarities to proteins of known function. Often functional clues of unknown proteins can be obtained by predicting small ligand molecules that bind to the proteins. METHODS: In our previo...

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Autori principali: Sael, Lee, Kihara , Daisuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375630/
https://ncbi.nlm.nih.gov/pubmed/22536870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S2-S7
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