Tax Protein-induced Expression of Antiapoptotic Bfl-1 Protein Contributes to Survival of Human T-cell Leukemia Virus Type 1 (HTLV-1)-infected T-cells

Human T lymphotropic virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL). ATLL is a severe malignancy with no effective treatment. HTLV-1 regulatory proteins Tax and HTLV-1 basic leucine zipper factor (HBZ) play a major role in ATLL development, by interfering with...

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Detalhes bibliográficos
Main Authors: Macaire, Héloïse, Riquet, Aurélien, Moncollin, Vincent, Biémont-Trescol, Marie-Claude, Duc Dodon, Madeleine, Hermine, Olivier, Debaud, Anne-Laure, Mahieux, Renaud, Mesnard, Jean-Michel, Pierre, Marlène, Gazzolo, Louis, Bonnefoy, Nathalie, Valentin, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375557/
https://ncbi.nlm.nih.gov/pubmed/22553204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340992
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