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Staphylococcus aureus CymR Is a New Thiol-based Oxidation-sensing Regulator of Stress Resistance and Oxidative Response

As a human pathogen, Staphylococcus aureus must cope with oxidative stress generated by the human immune system. Here, we report that CymR utilizes its sole Cys-25 to sense oxidative stress. Oxidation followed by thiolation of this cysteine residue leads to dissociation of CymR from its cognate prom...

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Detalhes bibliográficos
Main Authors: Ji, Quanjiang, Zhang, Liang, Sun, Fei, Deng, Xin, Liang, Haihua, Bae, Taeok, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375533/
https://ncbi.nlm.nih.gov/pubmed/22553203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359737
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