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Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus

Reductive deiodination is critical for thyroid function and represents an unusual exception to the more common oxidative and hydrolytic mechanisms of dehalogenation in mammals. Studies on the reductive processes have been limited by a lack of convenient methods for heterologous expression of the app...

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Autori principali: Buss, Jennifer M, McTamney, Patrick M, Rokita, Steven E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375436/
https://ncbi.nlm.nih.gov/pubmed/22238141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2020
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