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Evidence for Induction of Integron-Based Antibiotic Resistance by the SOS Response in a Clinical Setting

Bacterial resistance to β-lactams may rely on acquired β-lactamases encoded by class 1 integron-borne genes. Rearrangement of integron cassette arrays is mediated by the integrase IntI1. It has been previously established that integrase expression can be activated by the SOS response in vitro, leadi...

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Detalhes bibliográficos
Main Authors: Hocquet, Didier, Llanes, Catherine, Thouverez, Michelle, Kulasekara, Hemantha D., Bertrand, Xavier, Plésiat, Patrick, Mazel, Didier, Miller, Samuel I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375312/
https://ncbi.nlm.nih.gov/pubmed/22719259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002778
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