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Isolation of a Glucosamine Binding Leguminous Lectin with Mitogenic Activity towards Splenocytes and Anti-Proliferative Activity towards Tumor Cells

A dimeric 64-kDa glucosamine-specific lectin was purified from seeds of Phaseolus vulgaris cv. “brown kidney bean.” The simple 2-step purification protocol involved affinity chromatography on Affi-gel blue gel and gel filtration by FPLC on Superdex 75. The lectin was absorbed on Affi-gel blue gel an...

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Detalhes bibliográficos
Main Authors: Chan, Yau Sang, Wong, Jack Ho, Fang, Evandro Fei, Pan, Wenliang, Ng, Tzi Bun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375228/
https://ncbi.nlm.nih.gov/pubmed/22720002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038961
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