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Complex Spatial Dynamics of Oncolytic Viruses In Vitro: Mathematical and Experimental Approaches

Oncolytic viruses replicate selectively in tumor cells and can serve as targeted treatment agents. While promising results have been observed in clinical trials, consistent success of therapy remains elusive. The dynamics of virus spread through tumor cell populations has been studied both experimen...

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Detalhes bibliográficos
Main Authors: Wodarz, Dominik, Hofacre, Andrew, Lau, John W., Sun, Zhiying, Fan, Hung, Komarova, Natalia L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375216/
https://ncbi.nlm.nih.gov/pubmed/22719239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002547
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