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Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs

The purpose of this study was to determine the pharmacokinetics of phenytoin, theophylline, and diazepam in six healthy Greyhound dogs. Additionally the pharmacokinetics of the diazepam metabolites oxazepam and nordiazepam after diazepam administration were determined. Phenytoin sodium (12 mg/kg), a...

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Bibliografiske detaljer
Main Authors: KuKanich, Butch, Nauss, Jon L
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375049/
https://ncbi.nlm.nih.gov/pubmed/21692812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2885.2011.01316.x
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