Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer

There is an increasing understanding of the roles that microsatellite instability (MSI) plays in Lynch syndrome (by mutations) and sporadic (by mainly epigenetic changes) gastrointestinal (GI) and other cancers. Deficient DNA mismatch repair (MMR) results in the strong mutator phenotype known as MSI...

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Detalhes bibliográficos
Main Authors: Yamamoto, Hiroyuki, Adachi, Yasushi, Taniguchi, Hiroaki, Kunimoto, Hiroaki, Nosho, Katsuhiko, Suzuki, Hiromu, Shinomura, Yasuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2012
Assuntos:
Guidelines For Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374977/
https://ncbi.nlm.nih.gov/pubmed/22719182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i22.2745
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