An Open-Label Trial of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-1/rhIGFBP-3) in Myotonic Dystrophy Type 1

OBJECTIVE: To evaluate the safety and tolerability of recombinant human insulin-like growth factor-1 (rhIGF-1) complexed with IGF binding protein-3 (rhIGF-1/rhIGFBP-3) in patients with myotonic dystrophy type 1 (DM1). DESIGN: Open-label dose-escalation clinical trial. SETTING: University medical cen...

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Auteurs principaux: Heatwole, Chad R., Eichinger, Katy J., Friedman, Deborah I., Hilbert, James E., Jackson, Carlayne E., Logigian, Eric L., Martens, William B., McDermott, Michael P., Pandya, Shree K., Quinn, Christine, Smirnow, Alexis M., Thornton, Charles A., Moxley, Richard T.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374954/
https://ncbi.nlm.nih.gov/pubmed/20837825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2010.227
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