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The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo anti-malarial activity

Spilanthes spp. are used as traditional herbal medicines in Africa and India to treat malaria. Yet, to date, there is no data on active constituents or most effective extraction methods for this indication. The isolated alkylamides, spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, found...

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Bibliografiske detaljer
Main Authors: Spelman, Kevin, Depoix, Delphine, McCray, Megan, Mouray, Elisabeth, Grellier, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374932/
https://ncbi.nlm.nih.gov/pubmed/22692989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ptr.3395
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