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Radioiodinated Phenylalkyl Malonic Acid Derivatives as pH-Sensitive SPECT Tracers

INTRODUCTION: In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of apoptosis. METHODS: 2-(4-[(123)I]iodophene...

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Detalhes bibliográficos
Main Authors: Bauwens, Matthias, De Saint-Hubert, Marijke, Cleynhens, Jan, Brams, Laura, Devos, Ellen, Mottaghy, Felix M., Verbruggen, Alfons
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374791/
https://ncbi.nlm.nih.gov/pubmed/22719886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038428
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