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Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation

Solid tumors are frequently aneuploid, and many display high rates of ongoing chromosome missegregation in a phenomenon called chromosomal instability (CIN). The most common cause of CIN is the persistence of aberrant kinetochore-microtubule (k-MT) attachments, which manifest as lagging chromosomes...

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Detalhes bibliográficos
Main Authors: Hood, Emily A., Kettenbach, Arminja N., Gerber, Scott A., Compton, Duane A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374746/
https://ncbi.nlm.nih.gov/pubmed/22535524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1013
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