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Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation
Solid tumors are frequently aneuploid, and many display high rates of ongoing chromosome missegregation in a phenomenon called chromosomal instability (CIN). The most common cause of CIN is the persistence of aberrant kinetochore-microtubule (k-MT) attachments, which manifest as lagging chromosomes...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374746/ https://ncbi.nlm.nih.gov/pubmed/22535524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1013 |
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