Meox2Cre-mediated Disruption of CSF-1 Leads to Osteopetrosis and Osteocyte Defects

CSF-1, a key regulator of mononuclear phagocyte production, is highly expressed in the skeleton by osteoblasts/osteocytes and in a number of nonskeletal tissues such as uterus, kidney and brain. The spontaneous mutant op/op mouse has been the conventional model of CSF-1 deficiency and exhibits a ple...

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Huvudupphovsmän: Harris, Stephen E., MacDougall, Mary, Horn, Diane, Woodruff, Kathleen, Zimmer, Stephanie N., Rebel, Vivienne I., Fajardo, Roberto, Feng, Jian Q., Heinrich-Gluhak, Jelica, Harris, Marie A., Werner, Sherry Abboud
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374485/
https://ncbi.nlm.nih.gov/pubmed/21958845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2011.09.038
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