Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

Eukaryotic cells are equipped with an efficient quality control system to selectively eliminate misfolded and damaged proteins, and organelles. Abnormal polypeptides that escape from proteasome-dependent degradation and aggregate in the cytosol can be transported via microtubules to inclusion bodies...

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Detalhes bibliográficos
Main Authors: D'Eletto, M, Farrace, M G, Rossin, F, Strappazzon, F, Giacomo, G Di, Cecconi, F, Melino, G, Sepe, S, Moreno, S, Fimia, G M, Falasca, L, Nardacci, R, Piacentini, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374086/
https://ncbi.nlm.nih.gov/pubmed/22322858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.2
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