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Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation

Adult mammalian cells can be reprogrammed to a pluripotent state by forcing the expression of a few embryonic transcription factors. The resulting induced pluripotent stem (iPS) cells can differentiate into cells of all three germ layers. It is well known that post-natal cardiomyocytes (CMs) lack th...

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Autors principals: Rizzi, R, Di Pasquale, E, Portararo, P, Papait, R, Cattaneo, P, Latronico, M V G, Altomare, C, Sala, L, Zaza, A, Hirsch, E, Naldini, L, Condorelli, G, Bearzi, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374080/
https://ncbi.nlm.nih.gov/pubmed/22261617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.205
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