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Hydroxyurea for the Treatment of Sickle Cell Disease: Efficacy, Barriers, Toxicity, and Management in Children

Hydroxyurea is the only approved medication in the United States for the treatment of sickle cell anemia (HbSS) and is widely used in children despite an indication limited to adults. We review the evidence of efficacy and safety in children with reference to pivotal adult studies. This evidence and...

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Detalhes bibliográficos
Main Authors: Strouse, John J., Heeney, Matthew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374046/
https://ncbi.nlm.nih.gov/pubmed/22517797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24178
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