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Hydroxyurea for the Treatment of Sickle Cell Disease: Efficacy, Barriers, Toxicity, and Management in Children

Hydroxyurea is the only approved medication in the United States for the treatment of sickle cell anemia (HbSS) and is widely used in children despite an indication limited to adults. We review the evidence of efficacy and safety in children with reference to pivotal adult studies. This evidence and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Strouse, John J., Heeney, Matthew M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374046/
https://ncbi.nlm.nih.gov/pubmed/22517797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24178
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