Nevirapine- Versus Lopinavir/Ritonavir-Based Initial Therapy for HIV-1 Infection among Women in Africa: A Randomized Trial

BACKGROUND: Nevirapine (NVP) is widely used in antiretroviral treatment (ART) of HIV-1 globally. The primary objective of the AA5208/OCTANE trial was to compare the efficacy of NVP-based versus lopinavir/ritonavir (LPV/r)-based initial ART. METHODS AND FINDINGS: In seven African countries (Botswana,...

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Main Authors: Lockman, Shahin, Hughes, Michael, Sawe, Fred, Zheng, Yu, McIntyre, James, Chipato, Tsungai, Asmelash, Aida, Rassool, Mohammed, Kimaiyo, Sylvester, Shaffer, Douglas, Hosseinipour, Mina, Mohapi, Lerato, Ssali, Francis, Chibowa, Margret, Amod, Farida, Halvas, Elias, Hogg, Evelyn, Alston-Smith, Beverly, Smith, Laura, Schooley, Robert, Mellors, John, Currier, Judith
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373629/
https://ncbi.nlm.nih.gov/pubmed/22719231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001236
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