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LDL-Induced Impairment of Human Vascular Smooth Muscle Cells Repair Function Is Reversed by HMG-CoA Reductase Inhibition

Growing human atherosclerotic plaques show a progressive loss of vascular smooth muscle cells (VSMC) becoming soft and vulnerable. Lipid loaded-VSMC show impaired vascular repair function and motility due to changes in cytoskeleton proteins involved in cell-migration. Clinical benefits of statins re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Padró, Teresa, Lugano, Roberta, García-Arguinzonis, Maisa, Badimon, Lina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373563/
https://ncbi.nlm.nih.gov/pubmed/22719992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038935
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