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Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone
Premutation CGG repeat expansions (55–200 CGG repeats; preCGG) within the fragile X mental retardation 1 (FMR1) gene cause fragile X-associated tremor/ataxia syndrome (FXTAS). Defects in neuronal morphology and migration have been described in a preCGG mouse model. Mouse preCGG hippocampal neurons (...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373240/ https://ncbi.nlm.nih.gov/pubmed/22466801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds118 |
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