PULL-PUSH NEUROMODULATION OF LTP AND LTD ENABLES BIDIRECTIONAL EXPERIENCE-INDUCED SYNAPTIC SCALING IN VISUAL CORTEX

Neuromodulatory input, acting on G-protein coupled receptors, is essential for the induction of experience-dependent cortical plasticity. Here we report that G-coupled receptors in layer II/III of visual cortex control the polarity of synaptic plasticity through a pull-push regulation of LTP and LTD...

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Hauptverfasser: Treviño, Mario, Huang, ShiYong, He, Kaiwen, Ardiles, Alvaro, di Pasquale, Roberto, Guo, Yatu, Palacios, Adrian, Huganir, Richard, Kirkwood, Alfredo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373163/
https://ncbi.nlm.nih.gov/pubmed/22325202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.11.023
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