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Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network

Protein kinase D (PKD) binds to diacylglycerol (DAG) in the trans-Golgi network (TGN) and is activated by trimeric G-protein subunits βγ. This complex then regulates the formation of transport carriers in the TGN that traffic to the plasma membrane in non-polarized cells. Here we report specificity...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yeaman, Charles, Ayala, M. Inmaculada, Wright, Jessica R., Bard, Frederic, Bossard, Carine, Ang, Agnes, Maeda, Yusuke, Seufferlein, Thomas, Mellman, Ira, Nelson, W. James, Malhotra, Vivek
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372901/
https://ncbi.nlm.nih.gov/pubmed/14743217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1090
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