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Nesfatin-1(30–59) but not the N- and C-terminal fragments, nesfatin-1(1–29) and nesfatin-1(60–82) injected intracerebroventricularly decreases dark phase food intake by increasing inter-meal intervals in mice

Nesfatin-1 is an 82 amino acid N-terminal fragment of nucleobindin2 that was consistently shown to reduce dark phase food intake upon brain injection in rodents. We recently reported that nesfatin-1(1–82) injected intracerebroventricularly (icv) reduces dark phase feeding in mice. Moreover, intraper...

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Autores principales: Stengel, Andreas, Goebel-Stengel, Miriam, Wang, Lixin, Kato, Ikuo, Mori, Masatomo, Taché, Yvette
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372867/
https://ncbi.nlm.nih.gov/pubmed/22682899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2012.03.015
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