Helicobacter pylori infection upregulates interleukin-18 production from gastric epithelial cells

BACKGROUND: Helicobacter pylori infection induces a biased T helper type 1 (Th1) response that produces IFN-γ and Fas ligand (FasL). Th1 cytokines are associated with apoptosis in the gastric epithelial cells. AIM: We aimed to define the role of the recently cloned IL-18, a IFN-γ inducing factor, in...

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Autori principali: Shimada, Masaaki, Ando, Takafumi, Peek, Richard M., Watanabe, Osamu, Ishiguro, Kazuhiro, Maeda, Osamu, Ishikawa, Daisuke, Hasegawa, Motofusa, Ina, Kenji, Ohmiya, Naoki, Niwa, Yasumasa, Goto, Hidemi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372857/
https://ncbi.nlm.nih.gov/pubmed/18946358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MEG.0b013e32830edb15
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