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Role of endothelin-1 in the hyper-responsiveness to nitrovasodilators following acute NOS inhibition

BACKGROUND AND PURPOSE: Acute NOS inhibition in humans and animals is associated with hypersensitivity to NO donors. The mechanisms underlying this phenomenon have not been fully elucidated. The purpose of the present study was to assess whether hypersensitivity to NOS-blockade is linked to endothel...

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Detalhes bibliográficos
Main Authors: Bourque, Stephane L, Whittingham, Heather A, Brien, Susan E, Davidge, Sandra T, Adams, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372846/
https://ncbi.nlm.nih.gov/pubmed/21951225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01696.x
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