Histamine reduces susceptibility to natural killer cells via down-regulation of NKG2D ligands on human monocytic leukaemia THP-1 cells

Natural killer (NK) group 2D (NKG2D) is a key activating receptor expressed on NK cells, whose interaction with ligands on target cells plays an important role in tumorigenesis. However, the effect of histamine on NKG2D ligands on tumour cells is unclear. Here we showed that human monocytic leukaemi...

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Autori principali: Nagai, Yasuhiro, Tanaka, Yukinori, Kuroishi, Toshinobu, Sato, Ryutaro, Endo, Yasuo, Sugawara, Shunji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372762/
https://ncbi.nlm.nih.gov/pubmed/22304689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03565.x
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