β(2)-Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C-terminal tail

BACKGROUND AND PURPOSE: β-Adrenoceptor stimulation induces glucose uptake in several insulin-sensitive tissues by poorly understood mechanisms. EXPERIMENTAL APPROACH: We used a model system in CHO-K1 cells expressing the human β(2)-adrenoceptor and glucose transporter 4 (GLUT4) to investigate the si...

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Main Authors: Dehvari, Nodi, Hutchinson, Dana S, Nevzorova, Julia, Dallner, Olof S, Sato, Masaaki, Kocan, Martina, Merlin, Jon, Evans, Bronwyn A, Summers, Roger J, Bengtsson, Tore
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372728/
https://ncbi.nlm.nih.gov/pubmed/21883150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01647.x
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