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Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise

BACKGROUND AND PURPOSE: Depression is the most common psychiatric disorder in Huntington's disease (HD) patients. Women are more prone to develop depression and such susceptibility might be related to 5-hydroxytryptaminergic (serotonergic) dysregulation. EXPERIMENTAL APPROACH: We performed test...

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Main Authors: Renoir, Thibault, Pang, Terence YC, Zajac, Michelle S, Chan, Grace, Du, Xin, Leang, Leah, Chevarin, Caroline, Lanfumey, Laurence, Hannan, Anthony J
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372723/
https://ncbi.nlm.nih.gov/pubmed/21718306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01567.x
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