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Post-translational regulated and hypoxia-responsible VEGF plasmid for efficient secretion

Gene therapy using angiogenic genes has emerged as a potentially viable alternative treatment strategy for myocardial ischemia. Non-specific expression of angiogenic genes, however, may result in side effects, including the growth of occult tumors. Regulation of gene expression may help to avoid the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Won, Young-Wook, Lee, Minhyung, Ah Kim, Hyun, Bull, David A., Kim, Sung-Wan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372625/
https://ncbi.nlm.nih.gov/pubmed/22450332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.03.010
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