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Quercetin and Allopurinol Ameliorate Kidney Injury in STZ-Treated Rats with Regulation of Renal NLRP3 Inflammasome Activation and Lipid Accumulation

Hyperuricemia, hyperlipidemia and inflammation are associated with diabetic nephropathy. The NLRP3 inflammasome-mediated inflammation is recently recognized in the development of kidney injury. Urate and lipid are considered as danger signals in the NLRP3 inflammasome activation. Although dietary fl...

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Bibliografske podrobnosti
Main Authors: Wang, Chuang, Pan, Ying, Zhang, Qing-Yu, Wang, Fu-Meng, Kong, Ling-Dong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372527/
https://ncbi.nlm.nih.gov/pubmed/22701621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038285
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