Simvastatin Reduces Endotoxin-Induced Acute Lung Injury by Decreasing Neutrophil Recruitment and Radical Formation

INTRODUCTION: Treatment of acute lung injury (ALI) remains an unsolved problem in intensive care medicine. As simvastatin exerts protective effects in inflammatory diseases we explored its effects on development of ALI and due to the importance of neutrophils in ALI also on neutrophil effector funct...

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Autors principals: Grommes, Jochen, Vijayan, Santosh, Drechsler, Maik, Hartwig, Helene, Mörgelin, Matthias, Dembinski, Rolf, Jacobs, Michael, Koeppel, Thomas Andreas, Binnebösel, Marcel, Weber, Christian, Soehnlein, Oliver
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372465/
https://ncbi.nlm.nih.gov/pubmed/22701728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038917
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