Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces, Revealed the Extent and Complexity of the AdpA Regulatory Network

AdpA is a global transcriptional activator triggering morphological differentiation and secondary metabolism in Streptomyces griseus. AdpA influences the expression of >1000 genes; however, the overall picture of the AdpA regulon remains obscure. Here, we took snapshots of the distribution of Adp...

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Hlavní autoři: Higo, Akiyoshi, Hara, Hirofumi, Horinouchi, Sueharu, Ohnishi, Yasuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372375/
https://ncbi.nlm.nih.gov/pubmed/22449632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dss010
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