The Number of Toll-Like Receptor 9-Agonist Motifs in the Adenovirus Genome Correlates with Induction of Dendritic Cell Maturation by Adenovirus Immune Complexes

Adenovirus serotype 5 (Ad5) vectors and specific neutralizing antibodies (NAbs) generate immune complexes (ICs) which are potent inducers of dendritic cell (DC) maturation. Here we show that ICs generated with rare Ad vector serotypes, such as Ad26 and Ad35, which are lead candidates in HIV vaccine...

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Detalhes bibliográficos
Main Authors: Perreau, Matthieu, Welles, Hugh C., Pellaton, Celine, Gjoksi, Bebeka, Potin, Lambert, Martin, Ricardo, Harari, Alexandre, Bett, Andrew, Casimiro, Danilo, Gall, Jason, Barouch, Dan H., Kremer, Eric J., Pantaleo, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372176/
https://ncbi.nlm.nih.gov/pubmed/22491454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00123-12
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