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A microfluidic device for whole-animal drug screening using electrophysiological measures in the nematode C. elegans

This paper describes the fabrication and use of a microfluidic device for performing whole-animal chemical screens using non-invasive electrophysiological readouts of neuromuscular function in the nematode worm, C. elegans. The device consists of an array of microchannels to which electrodes are att...

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Détails bibliographiques
Auteurs principaux: Lockery, Shawn R., Hulme, S. Elizabeth, Roberts, William M., Robinson, Kristin J., Laromaine, Anna, Lindsay, Theodore H., Whitesides, George M., Weeks, Janis C.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372093/
https://ncbi.nlm.nih.gov/pubmed/22588281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2lc00001f
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