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Pathophysiological Role of Omega Pore Current in Channelopathies
In voltage-gated cation channels, a recurrent pattern for mutations is the neutralization of positively charged residues in the voltage-sensing S4 transmembrane segments. These mutations cause dominant ion channelopathies affecting many tissues such as brain, heart, and skeletal muscle. Recent studi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Research Foundation
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372090/ https://ncbi.nlm.nih.gov/pubmed/22701429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00112 |
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