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Why Do So Many Drugs for Alzheimer's Disease Fail in Development? Time for New Methods and New Practices?

Alzheimer's disease (AD) drug developments and clinical trials (CT) remain vulnerable to problems that undermine research validity. Investigations of CT methods reveal how numerous factors decrease active drug-placebo group differences and increase variance, thereby reducing power to reach stat...

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Bibliografische gegevens
Hoofdauteurs: Becker, Robert E., Greig, Nigel H., Giacobini, Ezio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372084/
https://ncbi.nlm.nih.gov/pubmed/18953116
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