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PSI-Search: iterative HOE-reduced profile SSEARCH searching
Summary: Iterative similarity searches with PSI-BLAST position-specific score matrices (PSSMs) find many more homologs than single searches, but PSSMs can be contaminated when homologous alignments are extended into unrelated protein domains—homologous over-extension (HOE). PSI-Search combines an op...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371869/ https://ncbi.nlm.nih.gov/pubmed/22539666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts240 |
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