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A hybrid approach to protein differential expression in mass spectrometry-based proteomics
Motivation: Quantitative mass spectrometry-based proteomics involves statistical inference on protein abundance, based on the intensities of each protein's associated spectral peaks. However, typical MS-based proteomics datasets have substantial proportions of missing observations, due at least...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371829/ https://ncbi.nlm.nih.gov/pubmed/22522136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts193 |
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