Inhibition of Cell Growth and Induction of Apoptosis by Antrodia camphorata in HER-2/neu-Overexpressing Breast Cancer Cells through the Induction of ROS, Depletion of HER-2/neu, and Disruption of the PI3K/Akt Signaling Pathway

Previously, we demonstrated that a submerged fermentation culture of Antrodia camphorata (AC) promotes cell-cycle arrest and apoptosis in human estrogen receptor-positive/negative breast cancer cells. However, whether AC is effective against HER-2/neu-overexpressing breast cancers has not been thoro...

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Main Authors: Lee, Chuan-Chen, Yang, Hsin-Ling, Way, Tzong-Der, Kumar, K. J. Senthil, Juan, Ying-Chen, Cho, Hsin-Ju, Lin, Kai-Yuan, Hsu, Li-Sung, Chen, Ssu-Ching, Hseu, You-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371823/
https://ncbi.nlm.nih.gov/pubmed/22701509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/702857
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