Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA

The complex relationship between DNA methylation, chromatin modification, and underlying DNA sequence is often difficult to unravel with existing technologies. Here, we describe a novel technique based on high-throughput sequencing of bisulfite-treated chromatin immunoprecipitated DNA (BisChIP-seq),...

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Main Authors: Statham, Aaron L., Robinson, Mark D., Song, Jenny Z., Coolen, Marcel W., Stirzaker, Clare, Clark, Susan J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371705/
https://ncbi.nlm.nih.gov/pubmed/22466171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.132076.111
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