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Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers

FA 2-hydroxylase (FA2H) is an NAD(P)H-dependent enzyme that initiates FA α oxidation and is also responsible for the biosynthesis of 2-hydroxy FA (2-OH FA)-containing sphingolipids in mammalian cells. The 2-OH FA is chiral due to the asymmetric carbon bearing the hydroxyl group. Our current study pe...

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Detalhes bibliográficos
Main Authors: Guo, Lin, Zhang, Xu, Zhou, Dequan, Okunade, Adewole L., Su, Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371244/
https://ncbi.nlm.nih.gov/pubmed/22517924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M025742
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