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Ehrlichia type IV secretion effector ECH0825 is translocated to mitochondria and curbs ROS and apoptosis by upregulating host MnSOD

Ehrlichia chaffeensis infects monocytes/macrophages and causes human monocytic ehrlichiosis. To determine the role of type IV secretion (T4S) system in infection, candidates for T4S effectors were identified by bacterial two-hybrid screening of E. chaffeensis hypothetical proteins with positively ch...

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Detalhes bibliográficos
Main Authors: Liu, Hongyan, Bao, Weichao, Lin, Mingqun, Niu, Hua, Rikihisa, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371182/
https://ncbi.nlm.nih.gov/pubmed/22348527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2012.01775.x
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