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Spatially restricted actin-regulatory signaling contributes to synapse morphology

The actin cytoskeleton in dendritic spines is organized into microdomains, but how signaling molecules that regulate actin are spatially governed is incompletely understood. Here we examine how the localization of the RacGEF kalirin-7, a well-characterized regulator of actin in spines, varies as a f...

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Autores principales: Nicholson, Daniel A., Cahill, Michael E., Tulisiak, Christopher T., Geinisman, Yuri, Penzes, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371164/
https://ncbi.nlm.nih.gov/pubmed/22458534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07743.x
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